Enzymes and Inhibitors
Bioworld 4-Methylumbelliferyl-á-D-Glucopyranoside, 1 g
4-Methylumbelliferyl-α-D-glucopyranoside[4-Methylumbelliferyl-α-D-Glucoside]C16H18O8MW 338.3Fluorescent substrate for -α-D-Glucosidase.Purity: >98%. 4-Methylumbelliferone <50ppm.Soluble in 2% acetone/water 1:1.CAS 17833-43-1This product is sold for laboratory research use only.
Echelon Biosciences Research Labs PTDINS DiC4 500 ug
Phosphatidylinositol diC4 (PI diC4) is a synthetic, purified dibutanoyl PI.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol. This item is non returnable
Cayman Chemical Lactate Substrate 1ea
A negative modulator of mitochondrial calcium uptake selectively decreases mitochondrial over cytosolic histamine-induced calcium uptake but also decreases the mitochondrial membrane potential in HeLa cells at 10 UM binds to Micu1 in a cell-free assay (Kd 8.4 UM for the mouse protein) decreases myotube width in differentiated C2C12 skeletal muscle myoblasts in an in vitro model of myotube growth protects against ferroptosis induced by RSL3 erastin or glutamate in HT22 hippocampal cells at 2.5 UM
Cayman Chemical Ascorbate Substrate 1ea
Morphine ELISA Standard has been tested and formulated to work exclusively with Cayman’s Morphine ELISA Kit (Item No. 501940).
Revvity Health Sciences Inc LANCE Ultra Phospho-PKC (A25S) Ulight Peptide Substrate, 0.5 nmole
LANCE Ultra Phospho-PKC (A25S) Ulight Peptide Substrate, 0.5 nmole
Medchemexpress LLC Ac-DEVD-AMC | 169332-61-0 | MFCD00671411 | 99.2% | 675.64 | 10 MG
Ac-DEVD-AMC is a fluorescent substrate for caspase-3/caspase-7. When treated with cell lysate, it releases amino-4-methylcoumarin (AMC) for fluorescence detection.
- Fluorescent substrate for caspase-3/caspase-7
- Releases amino-4-methylcoumarin (AMC) for fluorescence detection
- Excitation wavelength of 380 nm
- Emission wavelength of 460 nm
Bioworld IPTG (Isopropyl-B-D-ThioGalactopyranoside) Solution, 100mM, 10 mL
Isopropyl-β-D-Thiogalactopyranoside, an inducer of β-galactosidase is used to promote the expression of proteins in cells controlled by the lac operator system. Supplied as 1ml or 10x1ml of 100mM ready-to-use solution to be used with X-gal for blue white colony screening. Techncial Information:Biotechnology Grade.Ready-to-use solution Sterile filtered (0.22μM)Dioxane freeApplication: Petriplates: Use 40 μl per Petriplates (9 cm diameter). LB agar: Use 1μl/mL of liquid LB agar medium just before pouring (~50°C).Liquid culture: Use 1μl/mL of liquid culture medium.Sold as 1mL or 10 x 1mL.
![Alkali Scientific D Luciferin Sodium Salt [4,5 Dihydro 2 (6 hydroxy 2 benzothiazolyl) 4 thia zolecarboxylic acid, sodium salt], 100 Mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000659814.jpg-250.jpg)
Alkali Scientific D Luciferin Sodium Salt [4,5 Dihydro 2 (6 hydroxy 2 benzothiazolyl) 4 thia zolecarboxylic acid, sodium salt], 100 Mg
D-Luciferin Sodium Salt is a key substrate used in bioluminescence assays, particularly for detecting the activity of luciferase in biological systems. This reagent, in its sodium salt form, is used in laboratory applications to measure light emission through a reaction with the enzyme luciferase. The product is commonly used in applications such as gene expression studies, cell viability assays, and ATP detection. With its ability to generate light in the presence of luciferase, it provides an effective and highly sensitive method for biochemical assays. This 100mg bottle is ideal for laboratory-scale experimentation and analysis.
Medchemexpress LLC HER2/CD340 Human S 5ug | 5ug
The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics Upon activation it triggers the MEMO1-RHOA-DIAPH1 pathway inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization HER2/CD340 Protein Human (S310Y HEK293 His) is the recombinant human-derived HER2/CD340 protein expressed by HEK293 with C-10 His labeled tag and S310Y mutation
Medchemexpress LLC EGFR/HER2-IN-9 | 1637253-79-2 | C25H25ClFN5O4 | 5 MG
EGFR/HER2-IN-9 (Compound 1) is an EGFR and HER2 inhibitor for research use only.
- Inhibits EGFR with an IC50 of 3.2 nM
- Inhibits EGFR T790M with an IC50 of 8.3 nM
- Inhibits HER2 with an IC50 of 14 nM
Cayman Chemical G6PDH Substrate 1ea
A PARP1 and PARP2 inhibitor (IC50s 50s 1-14.1 nM) inhibits the proliferation of Capan-1 cells (IC50 0.1 nM) as well as talazoparib- or olaparib-resistant Capan-1 cells (IC50s 1.13 and 0.89 nM respectively) inhibits the proliferation of BRCA1 mutant HCC1937 breast cancer cells (IC50 4.54 nM) reduces tumor growth in an olaparib-resistant MDA-MB-436 breast cancer mouse xenograft model at 12.5 and 25 mg/kg
Medchemexpress LLC HER2/CD340 Human B 5ug | 5ug
The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics Upon activation it triggers the MEMO1-RHOA-DIAPH1 pathway inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization HER2/CD340 Protein Human (Biotinylated HEK293 His) is the recombinant human-derived Her2/CD340 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Z-DEVD-AFC | 1135416-11-3 | 98.1% | 821.71 | 10 MG
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence upon cleavage of the AFC fluorophore.
- Can be used to detect caspase-3-like enzyme activity.
- For research use only.
Medchemexpress LLC MBP-MAPK-Substrate | 138028-00-9 | 99.6% | 967.09 | 5 MG
MBP MAPK Substrate is utilized as an exogenous substrate for MAPK. It is intended for research use only, and not for sale to patients.
- Used as an exogenous substrate for MAPK
- Appearance: solid
- Color: white to off-white
- Sequence: Ala-Pro-Arg-Thr-Pro-Gly-Gly-Arg-R
- Sequence shortening: APRTPGGRR
- Target: p38 MAPK
- Pathway: MAPK/ERK pathway
![AdipoGen Ac-Ala-Asn-Trp-AMC [Ac-ANW-AMC], 2 mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501490625.PNG-250.jpg)
AdipoGen Ac-Ala-Asn-Trp-AMC [Ac-ANW-AMC], 2 mg
Ac-Ala-Asn-Trp-AMC [Ac-ANW-AMC] (2 mg), AdipoGen Life Sciences. Chemical. Formula: C30H32N6O7. MW: 588.6. Synthetic. Ac-ANW-AMC is a fluorogenic peptide substrate for measuring chymotrypsin-like activity of the immunoproteasome. Hydrolysis of this substrate by the beta5i-subunit of the immunoproteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This substrate is specific to the immunoproteasome and is not hydrolyzed efficiently by the constitutive proteasome.